Opportunity Information: Apply for RFA MH 25 116
The BRAIN Initiative: Marmoset Coordination Center (U24 Clinical Trials Not Allowed) funding opportunity (RFA-MH-25-116) is a National Institutes of Health (NIH) cooperative agreement designed to establish a centralized coordination hub for captive marmosets used in research. The core purpose is to strengthen the health, management, and long-term genetic diversity of marmoset colonies by building a shared infrastructure that brings together key records and uses them to guide responsible breeding decisions across participating primate colonies. Because this is a U24 cooperative agreement, the project is expected to involve substantial NIH involvement and coordination rather than operating like a typical investigator-initiated grant, and it is explicitly not intended for clinical trials.
A major responsibility of the awardee is to function as the primary repository for marmoset data that are essential for colony management and genetic stewardship. This includes genomic information, pedigree data, and event records such as dates of birth, medical history, and reproductive history. In practical terms, the center would serve as the trusted place where institutions can submit and maintain standardized records so that colony managers and researchers have a consistent, accurate picture of lineage, relatedness, and health trends over time. The emphasis on genomics and pedigree together signals that the center is expected to support modern genetic management, not just basic husbandry logs, and to help ensure that breeding plans are informed by both family structure and genetic variation.
In addition to holding the data, the center is expected to actively use these records to develop breeding recommendations aimed at maximizing overall colony health and preserving or improving genetic diversity. This implies a proactive coordination role: analyzing relatedness, identifying potential inbreeding risks, suggesting pairings that maintain diversity, and balancing genetic goals with health and reproductive considerations. The NOFO encourages applicants to adopt a model similar to the Association of Zoos and Aquariums (AZA), which is well known for structured population management approaches (for example, coordinated studbooks, standardized data practices, and decision-making frameworks that prioritize genetic diversity and population sustainability). The reference to AZA suggests NIH is looking for an organized, community-facing, best-practices-driven system rather than ad hoc recommendations.
Eligibility is broad and includes many domestic U.S. organization types typically allowed under NIH funding, such as state, county, city, and special district governments; public and private institutions of higher education; independent school districts; federally recognized tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofit organizations with and without 501(c)(3) status; for-profit organizations (other than small businesses) as well as small businesses; and other eligible entities. The NOFO also explicitly highlights additional categories of eligible applicants, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible agencies of the federal government, regional organizations, and U.S. territories or possessions.
At the same time, there are clear limits related to foreign participation. Non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components are allowed as defined in the NIH Grants Policy Statement, meaning a U.S.-based applicant can include certain foreign elements under NIH policy, but the applicant organization itself must be domestic and the project structure must comply with NIH rules on foreign components.
Administratively, the opportunity is categorized as discretionary and uses a cooperative agreement funding instrument. It falls under NIH and is associated with multiple CFDA numbers (93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, 93.867), reflecting its placement within NIH/BRAIN-related portfolios and accounting structures. The original closing date listed is 2024-03-01, and the opportunity record shows a creation date of 2023-11-28. The award ceiling and expected number of awards are not specified in the provided data, indicating applicants would need to consult the full NOFO for budget guidance, project period expectations, and any limits or recommended ranges.
Overall, this NOFO is about building a shared national-scale capability for marmoset colony coordination: collecting and maintaining standardized genomic and life-history data, using that information to guide breeding decisions, and creating a durable management framework modeled on proven zoological population management systems. The intended impact is a healthier, genetically diverse, and better-documented captive marmoset research population that can support high-quality neuroscience research under the BRAIN Initiative.Apply for RFA MH 25 116
- The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "BRAIN Initiative: Marmoset Coordination Center (U24 Clinical Trials Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, 93.867.
- This funding opportunity was created on 2023-11-28.
- Applicants must submit their applications by 2024-03-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
FAQs: The BRAIN Initiative - Marmoset Coordination Center (U24 Clinical Trials Not Allowed) (RFA-MH-25-116)
What is this funding opportunity?
This opportunity is an NIH cooperative agreement (U24) under the BRAIN Initiative to establish a centralized Marmoset Coordination Center. The center is intended to serve as a national-scale coordination hub for captive marmosets used in research.
What is the main purpose of the Marmoset Coordination Center?
The core purpose is to strengthen the health, management, and long-term genetic diversity of captive marmoset colonies by building shared infrastructure that consolidates key colony records and uses them to guide responsible breeding decisions across participating primate colonies.
Is this a standard NIH research grant?
No. This is a U24 cooperative agreement, which means the project is expected to include substantial NIH involvement and coordination. It is not intended to operate like a typical investigator-initiated grant.
Are clinical trials allowed under this opportunity?
No. The opportunity is explicitly designated as "Clinical Trials Not Allowed."
What kind of organization is expected to be funded?
The awardee is expected to function as a centralized coordination hub and primary repository for marmoset colony data used for colony management and genetic stewardship, and to use that information to develop breeding recommendations that support colony health and genetic diversity.
What is meant by a "centralized coordination hub" for marmosets?
It refers to a shared infrastructure where participating institutions can submit, maintain, and standardize essential colony records so colony managers and researchers have consistent, accurate information on lineage, relatedness, and health trends over time.
What types of data is the center expected to maintain?
The center is expected to serve as a primary repository for essential colony management and genetic stewardship data, including genomic information, pedigree data, and event records such as dates of birth, medical history, and reproductive history.
Why are both genomic and pedigree records emphasized?
The emphasis signals that NIH expects modern genetic management, not just basic husbandry logs. The intent is to support breeding plans informed by both family structure (pedigree) and genetic variation (genomics).
What are "event records" in this context?
Event records are life-history and management records such as dates of birth, medical history, and reproductive history that help track health and reproduction over time and support better-informed management decisions.
Is the center only responsible for storing data?
No. In addition to maintaining the data repository, the center is expected to actively use the records to develop breeding recommendations aimed at maximizing colony health and preserving or improving genetic diversity.
What does it mean to "develop breeding recommendations"?
It implies a proactive coordination role, such as analyzing relatedness, identifying potential inbreeding risks, suggesting pairings that maintain diversity, and balancing genetic goals with health and reproductive considerations.
What management model does NIH encourage applicants to follow?
The NOFO encourages a model similar to the Association of Zoos and Aquariums (AZA), which is known for structured population management approaches like coordinated studbooks, standardized data practices, and decision-making frameworks that prioritize genetic diversity and population sustainability.
Why is the AZA model referenced?
The reference suggests NIH is looking for an organized, community-facing, best-practices-driven system rather than ad hoc recommendations, with coordinated data practices and structured decision-making.
Who is eligible to apply?
Eligibility is broad and includes many domestic U.S. organization types typically allowed under NIH funding, including various levels of government, public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (other than small businesses) and small businesses, and other eligible entities.
Which government entities are eligible?
Eligible government entities include state, county, city, and special district governments, as well as eligible agencies of the federal government.
Are colleges and universities eligible?
Yes. Public and private institutions of higher education are eligible, and the NOFO also highlights several institution types such as HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and others.
Are nonprofit organizations eligible?
Yes. Nonprofit organizations with and without 501(c)(3) status are listed as eligible.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) and small businesses are listed as eligible.
Are tribal governments and tribal organizations eligible?
Yes. Federally recognized tribal governments are eligible, and tribal organizations that are not federally recognized are also listed as eligible.
Are faith-based or community-based organizations eligible?
Yes. The NOFO explicitly highlights faith-based or community-based organizations among additional categories of eligible applicants.
Are U.S. territories eligible?
Yes. U.S. territories or possessions are explicitly highlighted among additional eligible applicant categories.
Can a foreign (non-U.S.) organization apply?
No. Non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply.
Can a U.S. organization apply if the project includes a non-U.S. component?
Non-domestic components of U.S. organizations are not eligible to apply. However, foreign components are allowed as defined in the NIH Grants Policy Statement, meaning a U.S.-based applicant can include certain foreign elements if structured in compliance with NIH policy.
What is the funding instrument for this opportunity?
The funding instrument is a cooperative agreement (U24), and the opportunity is categorized as discretionary.
Which agency is offering this opportunity?
The opportunity is offered through the National Institutes of Health (NIH) and is associated with the BRAIN Initiative.
What is the opportunity number and title?
The opportunity is RFA-MH-25-116, titled "The BRAIN Initiative: Marmoset Coordination Center (U24 Clinical Trials Not Allowed)."
What CFDA numbers are associated with this opportunity?
The opportunity is associated with multiple CFDA numbers: 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, and 93.867.
When was this opportunity record created?
The opportunity record shows a creation date of 2023-11-28.
What is the listed closing date?
The original closing date listed is 2024-03-01.
How many awards will NIH make under this opportunity?
The expected number of awards is not specified in the provided information.
Is there an award ceiling or budget limit listed?
The award ceiling is not specified in the provided information. The summary indicates applicants would need to consult the full NOFO for budget guidance, project period expectations, and any limits or recommended ranges.
What is the intended impact of this award?
The intended impact is a healthier, genetically diverse, and better-documented captive marmoset research population that can support high-quality neuroscience research under the BRAIN Initiative.
Browse more opportunities from the same category: Education, Environment, Health, Income Security and Social Services
Next opportunity: Interplay of Autophagy Regulated Cell Death and HIV Pathogenesis in Substance Use Disorders (R01 Clinical Trial Not Allowed)
Previous opportunity: FY24 IIJA/IRA Bureau of Land Management Headquarters (HQ) Wildlife Program
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA MH 25 116
Applicants also applied for:
Applicants who have applied for this opportunity (RFA MH 25 116) also looked into and applied for these:
| Funding Opportunity |
|---|
| NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed) Apply for RFA NS 24 030 Funding Number: RFA NS 24 030 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Basic Experimental Studies with Humans Required) Apply for PA 24 186 Funding Number: PA 24 186 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Quantitative Research Development Award (Parent K25 Independent Basic Experimental Studies with Humans Required) Apply for PA 24 192 Funding Number: PA 24 192 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required) Apply for PA 24 181 Funding Number: PA 24 181 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Basic Experimental Studies with Humans Required) Apply for PA 24 183 Funding Number: PA 24 183 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Research Scientist Development Award (Parent K01 Independent Basic Experimental Studies with Humans Required) Apply for PA 24 177 Funding Number: PA 24 177 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Pathway to Independence Award (Parent K99/R00 Independent Basic Experimental Studies with Humans Required) Apply for PA 24 195 Funding Number: PA 24 195 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Small Business Transition Grant for New Entrepreneurs (R41/R42 Clinical Trial Not Allowed) Apply for PAR 24 133 Funding Number: PAR 24 133 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) Apply for PA 24 248 Funding Number: PA 24 248 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Basic Experimental Studies with Humans Required (BESH)) Apply for PAR 24 227 Funding Number: PAR 24 227 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Human Brain Single-cell Genomics Explorer (U24 - Clinical Trial Not Allowed) Apply for RFA NS 24 038 Funding Number: RFA NS 24 038 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $1,000,000 |
| Environmental Health Disparities Centers (P50) Clinical Trial Optional Apply for RFA MD 24 010 Funding Number: RFA MD 24 010 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) Apply for PAR 25 233 Funding Number: PAR 25 233 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Apply for PAR 25 143 Funding Number: PAR 25 143 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) Apply for PA 25 168 Funding Number: PA 25 168 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) Apply for PAR 25 298 Funding Number: PAR 25 298 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $375,000 |
| NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed) Apply for PA 25 302 Funding Number: PA 25 302 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed) Apply for PA 25 304 Funding Number: PA 25 304 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) Apply for PA 25 306 Funding Number: PA 25 306 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional) Apply for PAR 25 371 Funding Number: PAR 25 371 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA MH 25 116", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.